Introduction.The impaired proliferative capacity of alveolar epithelial cells after injury is an important factor causing epithelial repair dysfunction, leading to the occurrence of idiopathic pulmonary fibrosis (IPF).Alveolar type 2 (AT2) cells as the stem cells of alveolar epithelium participate in the repair process after alveolar injury.Lipocal
Abstract Local seed systems that are developed, managed and maintained by farmers are a fundamental practice in smallholder crop production, supporting more than 80% of farmers in sub-Saharan Africa and feeding more than 70% of its population.The resilience of such systems is under threat from poverty, climate change, drought, increased pests and d
The MARCH family of RING-finger E3 ubiquitin ligases comprise 11 members that have been reported to play a variety of roles in the downregulation of cell-surface proteins involved in adaptive immunity.The RING-CH domain of MARCH proteins is thought to ubiquitinate the cytoplasmic tails (CTs) of target proteins, leading to protein degradation throug
Background: Metastasis is the primary cause of cancer deaths, warranting further investigation.This study assessed microRNA-153 (miR-153) expression in bladder cancer tissues and investigated the underlying molecular mechanism of miR-153-mediated regulation of bladder cancer cells.Methods: Paired tissue specimens from 45 bladder cancer patients wer
One of the most critical challenges for modern power systems is to reliably supply electricity to its consumers during and figaro kaulaketju in the aftermath of natural disasters.As our dependence on electrical power has increased over the years, long-term power outages can lead to devastating impacts on affected communities.Furthermore, power outa